CG&D
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cell Growth & Differentiation

Right arrow Help viewing high resolution images
Right arrow Return to article


Fig. 3. PI3K signaling mediates specific expression of HIF-1{alpha} induced by EGF. PC-3 (A) and DU145 (B) cells were cultured in serum-free medium for 24 h. The PI3K inhibitors LY294002 and wortmannin were added at the indicated concentration 30 min before the addition of 20 ng/ml EGF. The cells were incubated in the presence (+) or absence (-) of EGF for 6 h. HIF-1{alpha} and HIF-1ß protein expression was analyzed as described above. The exposure times for immunoblots A and B were different, and the signals on these two blots are not comparable.





Right arrow Return to article


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cell Growth & Differentiation