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Fig. 2. Growth inhibition by IL-9 is correlated to the level of expression of the transfected receptor. A, IL-9R expression was measured in 11 BW5147 clones by flow cytometry with an anti-IL-9R antibody (6) . Growth inhibition by hIL-9 was measured as described in Fig. 1 and presented as a ratio between hexosaminidase levels in the absence and presence of IL-9. Linear correlation was calculated using InStat software. B, untransfected cells, clone 6, and clone 45 were stained with a hybrid protein consisting of a constant immunoglobulin {gamma}3 domain and either human (solid line) or murine (dashed line) IL-9 and with antimouse immunoglobulin antibodies coupled to FITC. Cells were analyzed by flow cytometry.





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HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cell Growth & Differentiation