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Fig. 7. Growth factor-activated pathways involved in p21 induction. On the basis of these results, p21 induction by FGF-2 occurs mainly independent of MEK1(/2) and Ras. PDGF, in contrast, requires MEK1(/2) to induce p21, whereas TGF-ß1 uses both Ras- and MEK1(/2)-dependent pathways.





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HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cell Growth & Differentiation