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Fig. 6. Mdm2 does not reduce E2F1/DP1 or pRB protein levels in cotransfected cells. A, effects of Mdm2 on the expression of wild-type p53, p53{Delta}I, E2F-1, or pRB. B, effects of Mdm2 on the expression of pRB, E2F-1, and DP-1 transfected in combination. Saos2 cells were cotransfected with plasmids encoding p53 (3 µg), E2F-1 (1 µg), RB (3 µg), and HA-DP-1(3 µg) with or without murine Mdm2 encoding plasmid (9 µg).





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HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cell Growth & Differentiation