Cell Growth & Differentiation, Vol 6, Issue 9 1193-1198, Copyright © 1995 by American Association of Cancer Research

ARTICLES

The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins

O Albagli, P Dhordain, C Deweindt, G Lecocq and D Leprince
Institut National de la Sante et de la Recherche Medicale U124-IRCL, Lille, France.

The BTB/POZ domain defines a newly characterized protein-protein interaction interface. It is highly conserved throughout metazoan evolution and generally found at the NH2 terminus of either actin-binding or, more commonly, nuclear DNA-binding proteins. By mediating protein binding in large aggregates, the BTB/POZ domain serves to organize higher order macromolecular complexes involved in ring canal formation or chromatin folding.

This article has been cited by other articles:

				Y.-H. Lin, H. O. Maaroufi, L. Kucerova, L. Rouhova, T. Filip, and M. Zurovec Adenosine receptor and its downstream targets, mod(mdg4) and Hsp70, work as a signaling pathway modulating cytotoxic damage in Drosophila bioRxiv, January 13, 2021; (2021) 2019.12.22.886143v5. [Abstract] [Full Text] [PDF]

				Z. A. Gibbs, L. C. Reza, C.-C. Cheng, J. M. Westcott, K. McGlynn, and A. W. Whitehurst The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGF{beta} signaling in triple-negative breast cancer bioRxiv, April 17, 2020; (2020) 2020.04.04.025742v2. [Abstract] [Full Text] [PDF]

				G. Wang Dopaminergic neurons mediate male Drosophila courtship motivational state bioRxiv, October 16, 2019; (2019) 733733v2. [Abstract] [Full Text] [PDF]

				Z. Xia, G. Xu, L. Nie, L. Liu, N. Peng, Q. He, Q. Zuo, Y. Zhou, Z. Cao, S. Liu, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1 J. Immunol., August 15, 2019; 203(4): 1001 - 1011. [Abstract] [Full Text] [PDF]

				T. Yamakawa, Y. Atsumi, S. Kubo, A. Yamagishi, I. Morita, and K. Matsuno Insight into Notch Signaling Steps That Involve pecanex from Dominant-Modifier Screens in Drosophila Genetics, August 1, 2018; 209(4): 1099 - 1119. [Abstract] [Full Text] [PDF]

				B. Bertocci, D. Lecoeuche, D. Sterlin, J. Kühn, B. Gaillard, A. De Smet, F. Lembo, C. Bole-Feysot, N. Cagnard, T. Fadeev, et al. Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation J. Immunol., October 1, 2017; 199(7): 2408 - 2420. [Abstract] [Full Text] [PDF]

				K. L. Yap, S. I. Fraley, M. M. Thiaville, N. Jinawath, K. Nakayama, J. Wang, T.-L. Wang, D. Wirtz, and I.-M. Shih NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells Cancer Res., August 15, 2012; 72(16): 4085 - 4096. [Abstract] [Full Text] [PDF]

				G. Boulay, M. Dubuissez, C. Van Rechem, A. Forget, K. Helin, O. Ayrault, and D. Leprince Hypermethylated in Cancer 1 (HIC1) Recruits Polycomb Repressive Complex 2 (PRC2) to a Subset of Its Target Genes through Interaction with Human Polycomb-like (hPCL) Proteins J. Biol. Chem., March 23, 2012; 287(13): 10509 - 10524. [Abstract] [Full Text] [PDF]

				S. Yao, M. Qian, S. Deng, L. Xie, H. Yang, C. Xiao, T. Zhang, H. Xu, X. Zhao, Y.-q. Wei, et al. Kzp Controls Canonical wnt8 Signaling to Modulate Dorsoventral Patterning during Zebrafish Gastrulation J. Biol. Chem., December 31, 2010; 285(53): 42086 - 42096. [Abstract] [Full Text] [PDF]

				D.-I. Koh, W.-I. Choi, B.-N. Jeon, C.-E. Lee, C.-O. Yun, and M.-W. Hur A Novel POK Family Transcription Factor, ZBTB5, Represses Transcription of p21CIP1 Gene J. Biol. Chem., July 24, 2009; 284(30): 19856 - 19866. [Abstract] [Full Text] [PDF]

				B.-N. Jeon, W.-I. Choi, M.-Y. Yu, A-R. Yoon, M.-H. Kim, C.-O. Yun, and M.-W. Hur ZBTB2, a Novel Master Regulator of the p53 Pathway J. Biol. Chem., July 3, 2009; 284(27): 17935 - 17946. [Abstract] [Full Text] [PDF]

				W.-I. Choi, B.-N. Jeon, C.-O. Yun, P.-H. Kim, S.-E. Kim, K.-Y. Choi, S. H. Kim, and M.-W. Hur Proto-oncogene FBI-1 Represses Transcription of p21CIP1 by Inhibition of Transcription Activation by p53 and Sp1 J. Biol. Chem., May 8, 2009; 284(19): 12633 - 12644. [Abstract] [Full Text] [PDF]

				M. Ishibashi, K. Nakayama, S. Yeasmin, A. Katagiri, K. Iida, N. Nakayama, and K. Miyazaki Expression of a BTB/POZ Protein, NAC1, Is Essential for the Proliferation of Normal Cyclic Endometrial Glandular Cells and Is Up-regulated by Estrogen Clin. Cancer Res., February 1, 2009; 15(3): 804 - 811. [Abstract] [Full Text] [PDF]

				S. Yeasmin, K. Nakayama, M. Ishibashi, A. Katagiri, K. Iida, I. N. Purwana, N. Nakayama, and K. Miyazaki Expression of the Bric-a-Brac Tramtrack Broad Complex Protein NAC-1 in Cervical Carcinomas Seems to Correlate with Poorer Prognosis Clin. Cancer Res., March 15, 2008; 14(6): 1686 - 1691. [Abstract] [Full Text] [PDF]

				S. Seng, H. K. Avraham, S. Jiang, S. Yang, M. Sekine, N. Kimelman, H. Li, and S. Avraham The Nuclear Matrix Protein, NRP/B, Enhances Nrf2-Mediated Oxidative Stress Responses in Breast Cancer Cells Cancer Res., September 15, 2007; 67(18): 8596 - 8604. [Abstract] [Full Text] [PDF]

				K. Nakayama, N. Nakayama, T.-L. Wang, and I.-M. Shih NAC-1 Controls Cell Growth and Survival by Repressing Transcription of Gadd45GIP1, a Candidate Tumor Suppressor Cancer Res., September 1, 2007; 67(17): 8058 - 8064. [Abstract] [Full Text] [PDF]

				U. V. Pedmale and E. Liscum Regulation of Phototropic Signaling in Arabidopsis via Phosphorylation State Changes in the Phototropin 1-interacting Protein NPH3 J. Biol. Chem., July 6, 2007; 282(27): 19992 - 20001. [Abstract] [Full Text] [PDF]

				S. Jiang, S. Seng, H. K. Avraham, Y. Fu, and S. Avraham Process Elongation of Oligodendrocytes Is Promoted by the Kelch-related Protein MRP2/KLHL1 J. Biol. Chem., April 20, 2007; 282(16): 12319 - 12329. [Abstract] [Full Text] [PDF]

				K. Nakayama, N. Nakayama, B. Davidson, J. J.-C. Sheu, N. Jinawath, A. Santillan, R. Salani, R. E. Bristow, P. J. Morin, R. J. Kurman, et al. A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival PNAS, December 5, 2006; 103(49): 18739 - 18744. [Abstract] [Full Text] [PDF]

				S. Seng, H. K. Avraham, S. Jiang, S. Venkatesh, and S. Avraham KLHL1/MRP2 Mediates Neurite Outgrowth in a Glycogen Synthase Kinase 3{beta}-Dependent Manner Mol. Cell. Biol., November 15, 2006; 26(22): 8371 - 8384. [Abstract] [Full Text] [PDF]

				Y. He, T. Zu, K. A. Benzow, H. T. Orr, H. B. Clark, and M. D. Koob Targeted Deletion of a Single Sca8 Ataxia Locus Allele in Mice Causes Abnormal Gait, Progressive Loss of Motor Coordination, and Purkinje Cell Dendritic Deficits J. Neurosci., September 27, 2006; 26(39): 9975 - 9982. [Abstract] [Full Text] [PDF]

				E. R. Tulman, G. Delhon, C. L. Afonso, Z. Lu, L. Zsak, N. T. Sandybaev, U. Z. Kerembekova, V. L. Zaitsev, G. F. Kutish, and D. L. Rock Genome of Horsepox Virus J. Virol., September 15, 2006; 80(18): 9244 - 9258. [Abstract] [Full Text] [PDF]

				T. Valenta, J. Lukas, L. Doubravska, B. Fafilek, and V. Korinek HIC1 attenuates Wnt signaling by recruitment of TCF-4 and {beta}-catenin to the nuclear bodies EMBO J., June 7, 2006; 25(11): 2326 - 2337. [Abstract] [Full Text] [PDF]

				D.-K. Lee, J.-E. Kang, H.-J. Park, M.-H. Kim, T.-H. Yim, J.-M. Kim, M.-K. Heo, K.-Y. Kim, H. J. Kwon, and M.-W. Hur FBI-1 Enhances Transcription of the Nuclear Factor-{kappa}B (NF-{kappa}B)-responsive E-selectin Gene by Nuclear Localization of the p65 Subunit of NF-{kappa}B J. Biol. Chem., July 29, 2005; 280(30): 27783 - 27791. [Abstract] [Full Text] [PDF]

				T. Emi, T. Kinoshita, K. Sakamoto, Y. Mineyuki, and K.-i. Shimazaki Isolation of a Protein Interacting with Vfphot1a in Guard Cells of Vicia faba Plant Physiology, July 1, 2005; 138(3): 1615 - 1626. [Abstract] [Full Text] [PDF]

				L. Heiska and O. Carpen Src Phosphorylates Ezrin at Tyrosine 477 and Induces a Phosphospecific Association between Ezrin and a Kelch-Repeat Protein Family Member J. Biol. Chem., March 18, 2005; 280(11): 10244 - 10252. [Abstract] [Full Text] [PDF]

				H. Kiefer, F. Chatail-Hermitte, P. Ravassard, E. Bayard, I. Brunet, and J. Mallet ZENON, a Novel POZ Kruppel-Like DNA Binding Protein Associated with Differentiation and/or Survival of Late Postmitotic Neurons Mol. Cell. Biol., March 1, 2005; 25(5): 1713 - 1729. [Abstract] [Full Text] [PDF]

				F. Piazza, J. A. Costoya, T. Merghoub, R. M. Hobbs, and P. P. Pandolfi Disruption of PLZP in Mice Leads to Increased T-Lymphocyte Proliferation, Cytokine Production, and Altered Hematopoietic Stem Cell Homeostasis Mol. Cell. Biol., December 1, 2004; 24(23): 10456 - 10469. [Abstract] [Full Text] [PDF]

				K. F. Kelly, A. A. Otchere, M. Graham, and J. M. Daniel Nuclear import of the BTB/POZ transcriptional regulator Kaiso J. Cell Sci., December 1, 2004; 117(25): 6143 - 6152. [Abstract] [Full Text] [PDF]

				C.-j. Liu, L. Prazak, M. Fajardo, S. Yu, N. Tyagi, and P. E. Di Cesare Leukemia/Lymphoma-related Factor, a POZ Domain-containing Transcriptional Repressor, Interacts with Histone Deacetylase-1 and Inhibits Cartilage Oligomeric Matrix Protein Gene Expression and Chondrogenesis J. Biol. Chem., November 5, 2004; 279(45): 47081 - 47091. [Abstract] [Full Text] [PDF]

				L. Melnikova, F. Juge, N. Gruzdeva, A. Mazur, G. Cavalli, and P. Georgiev Interaction between the GAGA factor and Mod(mdg4) proteins promotes insulator bypass in Drosophila PNAS, October 12, 2004; 101(41): 14806 - 14811. [Abstract] [Full Text] [PDF]

				S. Pinte, N. Stankovic-Valentin, S. Deltour, B. R. Rood, C. Guerardel, and D. Leprince The Tumor Suppressor Gene HIC1 (Hypermethylated in Cancer 1) Is a Sequence-specific Transcriptional Repressor: DEFINITION OF ITS CONSENSUS BINDING SEQUENCE AND ANALYSIS OF ITS DNA BINDING AND REPRESSIVE PROPERTIES J. Biol. Chem., September 10, 2004; 279(37): 38313 - 38324. [Abstract] [Full Text] [PDF]

				K. F. Kelly, C. M. Spring, A. A. Otchere, and J. M. Daniel NLS-dependent nuclear localization of p120ctn is necessary to relieve Kaiso-mediated transcriptional repression J. Cell Sci., June 1, 2004; 117(13): 2675 - 2686. [Abstract] [Full Text] [PDF]

				S. Tashiro, A. Muto, K. Tanimoto, H. Tsuchiya, H. Suzuki, H. Hoshino, M. Yoshida, J. Walter, and K. Igarashi Repression of PML Nuclear Body-Associated Transcription by Oxidative Stress-Activated Bach2 Mol. Cell. Biol., April 15, 2004; 24(8): 3473 - 3484. [Abstract] [Full Text] [PDF]

				T. Hara, H. Ishida, R. Raziuddin, S. Dorkhom, K. Kamijo, and T. Miki Novel Kelch-like Protein, KLEIP, Is Involved in Actin Assembly at Cell-Cell Contact Sites of Madin-Darby Canine Kidney Cells Mol. Biol. Cell, March 1, 2004; 15(3): 1172 - 1184. [Abstract] [Full Text] [PDF]

				F. Pessler and N. Hernandez Flexible DNA Binding of the BTB/POZ-domain Protein FBI-1 J. Biol. Chem., August 1, 2003; 278(31): 29327 - 29335. [Abstract] [Full Text] [PDF]

				W. Zhang, Y. Wang, J. Long, J. Girton, J. Johansen, and K. M. Johansen A Developmentally Regulated Splice Variant from the Complexlola Locus Encoding Multiple Different Zinc Finger Domain Proteins Interacts with the Chromosomal Kinase JIL-1 J. Biol. Chem., March 28, 2003; 278(13): 11696 - 11704. [Abstract] [Full Text] [PDF]

				M. Faucheux, J.- Y. Roignant, S. Netter, J. Charollais, C. Antoniewski, and L. Theodore batman Interacts with Polycomb and trithorax Group Genes and Encodes a BTB/POZ Protein That Is Included in a Complex Containing GAGA Factor Mol. Cell. Biol., February 15, 2003; 23(4): 1181 - 1195. [Abstract] [Full Text] [PDF]

				D. Piluso, P. Bilan, and J. P. Capone Host Cell Factor-1 Interacts with and Antagonizes Transactivation by the Cell Cycle Regulatory Factor Miz-1 J. Biol. Chem., November 29, 2002; 277(48): 46799 - 46808. [Abstract] [Full Text] [PDF]

				K. Sasagawa, Y. Matsudo, M. Kang, L. Fujimura, Y. Iitsuka, S. Okada, T. Ochiai, T. Tokuhisa, and M. Hatano Identification of Nd1, a Novel Murine Kelch Family Protein, Involved in Stabilization of Actin Filaments J. Biol. Chem., November 15, 2002; 277(46): 44140 - 44146. [Abstract] [Full Text] [PDF]

				R. Song, V. Llaca, and J. Messing Mosaic Organization of Orthologous Sequences in Grass Genomes Genome Res., October 1, 2002; 12(10): 1549 - 1555. [Abstract] [Full Text] [PDF]

				L. M. Zipper and R. T. Mulcahy The Keap1 BTB/POZ Dimerization Function Is Required to Sequester Nrf2 in Cytoplasm J. Biol. Chem., September 27, 2002; 277(39): 36544 - 36552. [Abstract] [Full Text] [PDF]

				D.-K. Lee, D. Suh, H. J. Edenberg, and M.-W. Hur POZ Domain Transcription Factor, FBI-1, Represses Transcription of ADH5/FDH by Interacting with the Zinc Finger and Interfering with DNA Binding Activity of Sp1 J. Biol. Chem., July 26, 2002; 277(30): 26761 - 26768. [Abstract] [Full Text] [PDF]

				S. Deltour, S. Pinte, C. Guerardel, B. Wasylyk, and D. Leprince The Human Candidate Tumor Suppressor Gene HIC1 Recruits CtBP through a Degenerate GLDLSKK Motif Mol. Cell. Biol., July 1, 2002; 22(13): 4890 - 4901. [Abstract] [Full Text] [PDF]

				A. Muto, S. Tashiro, H. Tsuchiya, A. Kume, M. Kanno, E. Ito, M. Yamamoto, and K. Igarashi Activation of Maf/AP-1 Repressor Bach2 by Oxidative Stress Promotes Apoptosis and Its Interaction with Promyelocytic Leukemia Nuclear Bodies J. Biol. Chem., June 7, 2002; 277(23): 20724 - 20733. [Abstract] [Full Text] [PDF]

				S. W. Kim, X. Fang, H. Ji, A. F. Paulson, J. M. Daniel, M. Ciesiolka, F. van Roy, and P. D. McCrea Isolation and Characterization of XKaiso, a Transcriptional Repressor That Associates with the Catenin Xp120ctn in Xenopus laevis J. Biol. Chem., March 8, 2002; 277(10): 8202 - 8208. [Abstract] [Full Text] [PDF]

				C. Mitchelmore, K. M. Kjaerulff, H. C. Pedersen, J. V. Nielsen, T. E. Rasmussen, M. F. Fisker, B. Finsen, K. M. Pedersen, and N. A. Jensen Characterization of Two Novel Nuclear BTB/POZ Domain Zinc Finger Isoforms: ASSOCIATION WITH DIFFERENTIATION OF HIPPOCAMPAL NEURONS, CEREBELLAR GRANULE CELLS, AND MACROGLIA J. Biol. Chem., March 1, 2002; 277(9): 7598 - 7609. [Abstract] [Full Text] [PDF]

				P. S. Pendergrast, C. Wang, N. Hernandez, and S. Huang FBI-1 Can Stimulate HIV-1 Tat Activity and Is Targeted to a Novel Subnuclear Domain that Includes the Tat-P-TEFb---containing Nuclear Speckles Mol. Biol. Cell, March 1, 2002; 13(3): 915 - 929. [Abstract] [Full Text] [PDF]

				A. G. West, M. Gaszner, and G. Felsenfeld Insulators: many functions, many mechanisms Genes & Dev., February 1, 2002; 16(3): 271 - 288. [Full Text] [PDF]

				K. Shim, K. J. Blake, J. Jack, and M. A. Krasnow The Drosophila ribbon gene encodes a nuclear BTB domain protein that promotes epithelial migration and morphogenesis Development, December 1, 2001; 128(23): 4923 - 4933. [Abstract] [Full Text] [PDF]

				J. O. Ward, M. J. McConnell, G. W. Carlile, P. P. Pandolfi, J. D. Licht, and L. P. Freedman The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D3-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D3 receptor Blood, December 1, 2001; 98(12): 3290 - 3300. [Abstract] [Full Text] [PDF]

				W. Wei and M. D. Brennan The gypsy Insulator Can Act as a Promoter-Specific Transcriptional Stimulator Mol. Cell. Biol., November 15, 2001; 21(22): 7714 - 7720. [Abstract] [Full Text] [PDF]

				E. Nili, G. S. Cojocaru, Y. Kalma, D. Ginsberg, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, R. Berger, S. Shaklai, N. Amariglio, et al. Nuclear membrane protein LAP2{beta} mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less) J. Cell Sci., September 15, 2001; 114(18): 3297 - 3307. [Abstract] [Full Text] [PDF]

				A. Anand, A. Villella, L. C. Ryner, T. Carlo, S. F. Goodwin, H.-J. Song, D. A. Gailey, A. Morales, J. C. Hall, B. S. Baker, et al. Molecular Genetic Dissection of the Sex-Specific and Vital Functions of the Drosophila melanogaster Sex Determination Gene fruitless Genetics, August 1, 2001; 158(4): 1569 - 1595. [Abstract] [Full Text] [PDF]

				T. Collins, J. R. Stone, and A. J. Williams All in the Family: the BTB/POZ, KRAB, and SCAN Domains Mol. Cell. Biol., June 1, 2001; 21(11): 3609 - 3615. [Full Text] [PDF]

				R. Kanezaki, T. Toki, M. Yokoyama, K. Yomogida, K. Sugiyama, M. Yamamoto, K. Igarashi, and E. Ito Transcription Factor BACH1 Is Recruited to the Nucleus by Its Novel Alternative Spliced Isoform J. Biol. Chem., March 9, 2001; 276(10): 7278 - 7284. [Abstract] [Full Text] [PDF]

				C. Guerardel, S. Deltour, S. Pinte, D. Monte, A. Begue, A. K. Godwin, and D. Leprince Identification in the Human Candidate Tumor Suppressor GeneHIC-1 of a New Major Alternative TATA-less Promoter Positively Regulated by p53 J. Biol. Chem., February 2, 2001; 276(5): 3078 - 3089. [Abstract] [Full Text] [PDF]

				A. Melnick, K. F. Ahmad, S. Arai, A. Polinger, H. Ball, K. L. Borden, G. W. Carlile, G. G. Prive, and J. D. Licht In-Depth Mutational Analysis of the Promyelocytic Leukemia Zinc Finger BTB/POZ Domain Reveals Motifs and Residues Required for Biological and Transcriptional Functions Mol. Cell. Biol., September 1, 2000; 20(17): 6550 - 6567. [Abstract] [Full Text] [PDF]

				Y. Wen, D. Nguyen, Y. Li, and Z.-C. Lai The N-terminal BTB/POZ Domain and C-Terminal Sequences Are Essential for Tramtrack69 to Specify Cell Fate in the Developing Drosophila Eye Genetics, September 1, 2000; 156(1): 195 - 203. [Abstract] [Full Text] [PDF]

				S. A. Mackler, L. Korutla, X.-Y. Cha, M. J. Koebbe, K. M. Fournier, M. S. Bowers, and P. W. Kalivas NAC-1 Is a Brain POZ/BTB Protein That Can Prevent Cocaine-Induced Sensitization in the Rat J. Neurosci., August 15, 2000; 20(16): 6210 - 6217. [Abstract] [Full Text] [PDF]

				K. D. Huynh, W. Fischle, E. Verdin, and V. J. Bardwell BCoR, a novel corepressor involved in BCL-6 repression Genes & Dev., July 15, 2000; 14(14): 1810 - 1823. [Abstract] [Full Text]

				H. Peng, G. E. Begg, S. L. Harper, J. R. Friedman, D. W. Speicher, and F. J. Rauscher III Biochemical Analysis of the Kruppel-associated Box (KRAB) Transcriptional Repression Domain: SPECTRAL, KINETIC, AND STOICHIOMETRIC PROPERTIES OF THE KRAB{middle dot}KAP-1 COMPLEX J. Biol. Chem., June 16, 2000; 275(24): 18000 - 18010. [Abstract] [Full Text] [PDF]

				L. Zhao, F. Gregoire, and H. Sook Sul Transient Induction of ENC-1, a Kelch-related Actin-binding Protein, Is Required for Adipocyte Differentiation J. Biol. Chem., June 2, 2000; 275(22): 16845 - 16850. [Abstract] [Full Text] [PDF]

				C. Schumacher, H. Wang, C. Honer, W. Ding, J. Koehn, Q. Lawrence, C. M. Coulis, L. L. Wang, D. Ballinger, B. R. Bowen, et al. The SCAN Domain Mediates Selective Oligomerization J. Biol. Chem., June 2, 2000; 275(22): 17173 - 17179. [Abstract] [Full Text] [PDF]

				P. Z. Anastasiadis and A. B. Reynolds The p120 catenin family: complex roles in adhesion, signaling and cancer J. Cell Sci., April 15, 2000; 113(8): 1319 - 1334. [Abstract] [PDF]

				A. Kobayashi, H. Yamagiwa, H. Hoshino, A. Muto, K. Sato, M. Morita, N. Hayashi, M. Yamamoto, and K. Igarashi A Combinatorial Code for Gene Expression Generated by Transcription Factor Bach2 and MAZR (MAZ-Related Factor) through the BTB/POZ Domain Mol. Cell. Biol., March 1, 2000; 20(5): 1733 - 1746. [Abstract] [Full Text] [PDF]

				S. F. Goodwin, B. J. Taylor, A. Villella, M. Foss, L. C. Ryner, B. S. Baker, and J. C. Hall Aberrant Splicing and Altered Spatial Expression Patterns in fruitless Mutants of Drosophila melanogaster Genetics, February 1, 2000; 154(2): 725 - 745. [Abstract] [Full Text] [PDF]

				T. Sakai, T. Wada, S. Ishiguro, and K. Okada RPT2: A Signal Transducer of the Phototropic Response in Arabidopsis PLANT CELL, February 1, 2000; 12(2): 225 - 236. [Abstract] [Full Text] [PDF]

				S. Deltour, C. Guerardel, and D. Leprince Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: The case of HIC-1 and gamma FBP-B PNAS, December 21, 1999; 96(26): 14831 - 14836. [Abstract] [Full Text] [PDF]

				Z.-G. Han, Q.-H. Zhang, M. Ye, L.-X. Kan, B.-W. Gu, K.-L. He, S.-L. Shi, J. Zhou, G. Fu, M. Mao, et al. Molecular Cloning of Six Novel Kruppel-like Zinc Finger Genes from Hematopoietic Cells and Identification of a Novel Transregulatory Domain KRNB J. Biol. Chem., December 10, 1999; 274(50): 35741 - 35748. [Abstract] [Full Text] [PDF]

				H. Stenmark and R. Aasland FYVE-finger proteins--effectors of an inositol lipid J. Cell Sci., December 1, 1999; 112(23): 4175 - 4183. [Abstract] [PDF]

				M. E. Hoatlin, Y. Zhi, H. Ball, K. Silvey, A. Melnick, S. Stone, S. Arai, N. Hawe, G. Owen, A. Zelent, et al. A Novel BTB/POZ Transcriptional Repressor Protein Interacts With the Fanconi Anemia Group C Protein and PLZF Blood, December 1, 1999; 94(11): 3737 - 3747. [Abstract] [Full Text] [PDF]

				A. Motchoulski and E. Liscum Arabidopsis NPH3: A NPH1 Photoreceptor-Interacting Protein Essential for Phototropism Science, October 29, 1999; 286(5441): 961 - 964. [Abstract] [Full Text]

				X. Li, H. Peng, D. C. Schultz, J. M. Lopez-Guisa, F. J. Rauscher III, and R. Marmorstein Structure-Function Studies of the BTB/POZ Transcriptional Repression Domain from the Promyelocytic Leukemia Zinc Finger Oncoprotein Cancer Res., October 1, 1999; 59(20): 5275 - 5282. [Abstract] [Full Text] [PDF]

				M. Soltysik-Espanola, R. A. Rogers, S. Jiang, T.-A. Kim, R. Gaedigk, R. A. White, H. Avraham, and S. Avraham Characterization of Mayven, a Novel Actin-binding Protein Predominantly Expressed in Brain Mol. Biol. Cell, July 1, 1999; 10(7): 2361 - 2375. [Abstract] [Full Text]

				R. F. Ryan, D. C. Schultz, K. Ayyanathan, P. B. Singh, J. R. Friedman, W. J. Fredericks, and F. J. Rauscher III KAP-1 Corepressor Protein Interacts and Colocalizes with Heterochromatic and Euchromatic HP1 Proteins: a Potential Role for Krüppel-Associated Box-Zinc Finger Proteins in Heterochromatin-Mediated Gene Silencing Mol. Cell. Biol., June 1, 1999; 19(6): 4366 - 4378. [Abstract] [Full Text] [PDF]

				A. Melnick and J. D. Licht Deconstructing a Disease: RAR{alpha}, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia Blood, May 15, 1999; 93(10): 3167 - 3215. [Full Text] [PDF]

				J. M. Daniel and A. B. Reynolds The Catenin p120ctnInteracts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor Mol. Cell. Biol., May 1, 1999; 19(5): 3614 - 3623. [Abstract] [Full Text] [PDF]

				R. J. Jackson, D. F. Hall, and P. J. Kerr Myxoma Virus Encodes an {alpha}2,3-Sialyltransferase That Enhances Virulence J. Virol., March 1, 1999; 73(3): 2376 - 2384. [Abstract] [Full Text] [PDF]

				S. de la Luna, K. E. Allen, S. L. Mason, and N. B. La Thangue Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor EMBO J., January 4, 1999; 18(1): 212 - 228. [Abstract] [Full Text] [PDF]

				C.-M. Tang, J. Westling, and E. Seto trans Repression of the Human Metallothionein IIA Gene Promoter by PZ120, a Novel 120-Kilodalton Zinc Finger Protein Mol. Cell. Biol., January 1, 1999; 19(1): 680 - 689. [Abstract] [Full Text] [PDF]

				K. Itoh, N. Wakabayashi, Y. Katoh, T. Ishii, K. Igarashi, J. D. Engel, and M. Yamamoto Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain Genes & Dev., January 1, 1999; 13(1): 76 - 86. [Abstract] [Full Text]

				M. Lehmann, T. Siegmund, K.-G. Lintermann, and G. Korge The Pipsqueak Protein of Drosophila melanogasterBinds to GAGA Sequences through a Novel DNA-binding Domain J. Biol. Chem., October 23, 1998; 273(43): 28504 - 28509. [Abstract] [Full Text] [PDF]

				K. F. Ahmad, C. K. Engel, and G. G. Prive Crystal structure of the BTB domain from PLZF PNAS, October 13, 1998; 95(21): 12123 - 12128. [Abstract] [Full Text] [PDF]

				K. Aoki, G. Meng, K. Suzuki, T. Takashi, Y. Kameoka, K. Nakahara, R. Ishida, and M. Kasai RP58 Associates with Condensed Chromatin and Mediates a Sequence-specific Transcriptional Repression J. Biol. Chem., October 9, 1998; 273(41): 26698 - 26704. [Abstract] [Full Text] [PDF]

				A. Muto, H. Hoshino, L. Madisen, N. Yanai, M. Obinata, H. Karasuyama, N. Hayashi, H. Nakauchi, M. Yamamoto, M. Groudine, et al. Identification of Bach2 as a B-cell-specific partner for small Maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer EMBO J., October 1, 1998; 17(19): 5734 - 5743. [Abstract] [Full Text] [PDF]

				T. Wolff, R. E. ONeill, and P. Palese NS1-Binding Protein (NS1-BP): a Novel Human Protein That Interacts with the Influenza A Virus Nonstructural NS1 Protein Is Relocalized in the Nuclei of Infected Cells J. Virol., September 1, 1998; 72(9): 7170 - 7180. [Abstract] [Full Text] [PDF]

				R. Shaknovich, P. L. Yeyati, S. Ivins, A. Melnick, C. Lempert, S. Waxman, A. Zelent, and J. D. Licht The Promyelocytic Leukemia Zinc Finger Protein Affects Myeloid Cell Growth, Differentiation, and Apoptosis Mol. Cell. Biol., September 1, 1998; 18(9): 5533 - 5545. [Abstract] [Full Text] [PDF]

				M. R. Dow and P. E. Mains Genetic and Molecular Characterization of the Caenorhabditis elegans Gene, mel-26, a Postmeiotic Negative Regulator of MEI-1, a Meiotic-Specific Spindle Component Genetics, September 1, 1998; 150(1): 119 - 128. [Abstract] [Full Text] [PDF]

				S. Okabe, T. Fukuda, K. Ishibashi, S. Kojima, S. Okada, M. Hatano, M. Ebara, H. Saisho, and T. Tokuhisa BAZF, a Novel Bcl6 Homolog, Functions as a Transcriptional Repressor Mol. Cell. Biol., July 1, 1998; 18(7): 4235 - 4244. [Abstract] [Full Text] [PDF]

				H. Niu, B. H. Ye, and R. Dalla-Favera Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor Genes & Dev., July 1, 1998; 12(13): 1953 - 1961. [Abstract] [Full Text]

				K. Igarashi, H. Hoshino, A. Muto, N. Suwabe, S. Nishikawa, H. Nakauchi, and M. Yamamoto Multivalent DNA Binding Complex Generated by Small Maf and Bach1 as a Possible Biochemical Basis for {beta}-Globin Locus Control Region Complex J. Biol. Chem., May 8, 1998; 273(19): 11783 - 11790. [Abstract] [Full Text] [PDF]

				T.-A. Kim, J. Lim, S. Ota, S. Raja, R. Rogers, B. Rivnay, H. Avraham, and S. Avraham NRP/B, a Novel Nuclear Matrix Protein, Associates With p110RB and Is Involved in Neuronal Differentiation J. Cell Biol., May 4, 1998; 141(3): 553 - 566. [Abstract] [Full Text] [PDF]