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Cell Growth & Differentiation, Vol 6, Issue 10 1307-1314, Copyright © 1995 by American Association of Cancer Research

ARTICLES

Induction of stathmin expression during erythropoietic differentiation

T Rabilloud, R Berthier, C Valette, J Garin and JJ Lawrence
Laboratoire de Biologie Moleculaire du Cycle Cellulaire, INSERM U309, CEA-DBMS, Grenoble, France.

Stathmin is a M(r) 19,000 cytosolic protein proposed to act as a relay for signal-activating pathways regulating cell proliferation and differentiation. In a study of erythropoietic differentiation, stathmin was detected as a protein that is induced during the early stages of differentiation in several cellular model systems. The unphosphorylated form of stathmin was most prominently induced, which suggests that this form does not only play a role in pathways oriented toward cell proliferation, as is the case for lymphocytic systems, but may also play a role in various differentiation pathways.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cell Growth & Differentiation
Copyright © 1995 by the American Association of Cancer Research.