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Fig. 10. Time course showing the effect of 15d-PGJ2 treatment on cyclin D1 protein expression in wild-type and PKR-null mouse embryo fibroblast cells. Wild-type (Pkr+/+) or PKR-null (Pkr0/0) cells were treated for the indicated period of time with 20 µM 15d-PGJ2. Cyclin D1 protein levels were determined by Western immunoblot analysis.