Click on image to view larger version.



Fig. 1. EGFR protein levels correlate with constitutive STAT3 activation levels in eight representative SCCHN cell lines. Immunoblotting (A) and EMSA (B) showing EGFR protein expression and corresponding constitutive STAT3 activation in SCCHN cell lines. The SIF-A band represents STAT3 homodimers. C, scatterplot showing correlation of EGFR protein expression levels and STAT3 activation levels in eight SCCHN cell lines (r = 0.905, p = 0.02).