Table 1 Fatty acid composition of Jurkat and derived hyperproliferative sublines

Data are expressed as percentage (by weight) of the total cellular fatty acids and are the mean ± SD of results obtained in three different experiments with samples analyzed in duplicate.

Fatty acid Jurkat Jurkat-ws Jurkat-hp

14:0 2.0 ± 0.1 3.2 ± 0.5 3.5 ± 0.1
14:1 1.1 ± 0.1 0.4 ± 0.1 n.d.a
16:0DMA 1.7 ± 0.2 0.7 ± 0.1 n.d.
16:0 27.2 ± 0.1 17.1 ± 0.4 25.1 ± 0.6
16:1(n-9) 3.0 ± 0.1 0.7 ± 0.1 n.d.
16:1(n-7) 2.8 ± 0.1 12.9 ± 0.8 11.6 ± 0.7
18:0 15.9 ± 1.6 8.2 ± 0.7 10.0 ± 0.5
18:1(n-9) 21.6 ± 0.1 30.7 ± 2.0 33.2 ± 0.9
18:1(n-7) 8.2 ± 0.1 19.4 ± 1.5 13.8 ± 0.7
18:2(n-6) 2.3 ± 0.5 n.d. 1.4 ± 0.1
20:1(n-9) 1.1 ± 0.1 1.2 ± 0.1 n.d.
20:1(n-7) n.d. 1.6 ± 0.1 n.d.
20:4(n-6) 7.1 ± 0.7 n.d. 1.0 ± 0.1
22:4(n-6) n.d. n.d. n.d.
22:5(n-6) n.d. n.d. n.d.
22:6(n-3) 4.7 ± 0.2 n.d. n.d.
µg FA/106 cells 7.8 ± 0.2 3.2 ± 0.3 6.6 ± 0.7
Ratio polyunsaturates: monounsaturates 0.37 0.00 0.04

a n.d., not detected, DMA, dimethyl acetal from alkenyl side chains of plasmalogens.