Fig. 1. Top panel, Western blot analysis of human CDC34 protein expression in a representative set of five pre-B-cell ALL(Lanes 15) and T-cell ALL (Lanes 610) samples. Middle panel, results of hybridization of the same membrane with anti ß-actin antibody. The sample in Lane 3 is a pre-B-cell ALL sample that expresses both lymphoid and myeloid markers on immunophenotype analysis. Lower panel, Northern blot analysis of total RNA from the same samples as shown in top panel using a 32P-labeled human CDC34 probe.