Fig. 5. CIITA promoter IV IRF-E activity in melanoma and melanocyte cells. The wild-type CIITA P4/-85 promoter luciferase construct and a mutant CIITA P4/-85 promoter luciferase construct with a mutant IRF-E were transiently transfected into cells as indicated. Luciferase activity was assayed 48 h after transfection.