Fig. 1. Prostate epithelial spheroids grown in Matrigel and KSFM (sample C). A, phase image. Bar, 80 µm, the approximate diameter of one spheroid. B, TEM of a whole spheroid. Bar, 10 µm. C, high magnification TEM indicating both tight (TJ) and desmosomal-like (D) junctions present between the tightly associating inner cells. Bar, 0.5 µm. D, a line drawing representing C to indicate the exact location and appearance of the tight and desmosomal-like junctions.