Table 1 Double-stranded oligonucleotides

Oligomer Sequencea

PRE1 WT -219-GTTACTTTGTGAACTGTGCACTTAGTCATTCTTGAGTA-180
PRE1 M4 -219-GTTACTTTGTGACAGTTGCACTTAGTCATTCTTGAGTA-180
PRE1 M7 -219-GTTACTTTGTGAACTGTGCACTGCTGCATTCTTGAGTA-180
CCAAT-WT -100-GGCTGGTCTAGGAAACATGATTGGCAGCTACGAG-67
CCAAT-R -100-GGCTGGTCTAGGAAACATGCCAATCAGCTACGAG-67
CCAAT-M -100-GGCTGGTCTAGGAAACATGAGGTTCAGCTACGAG-67
PRE2 WT +2-GTTGGCGAGGAGTTTCCTGTTTCCCCCGCAGCGCTG-+36
PRE2 M4 +2-GTTGGCGAGGAGTTTAAGTGTTCCCCCGCAGCGCTG-+36

a Base pairs in bold and underlined represent the core sequence for the API/ATF-2-like sequence, inverted CCAAT box, and ETS binding site, respectively. Base pairs in bold represent the specific mutations in each oligonucleotide.