Table 1 Cell cycle analysis of K562 cells and clones C1 and C4

Cell cycle analysis of K562 cells and two clones derived by mutation of K562 was carried out as described in "Materials and Methods." Cells were fixed and labeled with propidium iodide, and staining was obtained by fluorescence-activated cell-sorting analysis as described in "Materials and Methods."

Cell line PMAa G1 S phase G2-M phase

Wild-type K562 cells - 40 51.6 8.2
+ 69.4 14.1 16.5
C1 - 36.2 52 11.8
+ 25.7 62.8 11.5
C4 - 34.4 53.3 12.2
+ 32.9 59.2 7.2

a Analysis was carried out after 36 h of PMA treatment.