Fig. 1. dnPLK1 induces selective apoptosis in tumor cells versus normal cells. Cells were infected at 500 MOI of dnPLK1 and processed for FACS analysis at different time points. Percentage increase in Sub-2N is calculated from % dnPLK Ad - % control Ad. Fold > Sub-2N is calculated from % dnPLK ÷ % control Ad. DN/WT, the ratio of protein expression determined from the dilution of dnPLK1-expressing lysate that gave equivalent expression to control virus-infected samples 24 h postinfection.